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港人壓力大,抑鬱症越趨普遍。若確診抑鬱症,患者有需要服用多種抗抑鬱藥物,必要時或需加大劑量。當服用兩種或以上一定劑量的抗抑鬱藥物,並持續一段時間,治療效果卻不甚理想時,醫學上便稱為「難治型抑鬱症」。統計顯示,有關病人佔抑鬱症患者多達三分一,絕對不容忽視。

現時醫學界積極發開發針對谷氨酸系統 (glutamate)的新抗抑鬱藥物。透過雙管齊下的藥物治療方案,對比過去30年的主要透過調節大腦中單胺系統(monoamine)抗抑鬱藥物,包括血清素多巴胺去甲腎上腺素的信號傳遞療法,臨床所見平均大約服用二至三星期才見效,而且並非對所有抑鬱症患者都能奏效之下,患者使用針對谷氨酸系統 (glutamate)的新抗抑鬱藥物有望在更短時間內減輕抑鬱情緒,得到緩解。

抑鬱症有多種治療方案,各有其成效、副作用及限制,患者應與自己的主診醫生商討,選用最合適的治療方案。若出現抑鬱症症狀便應儘早求助及求醫,及早治療處理症狀。

若想了解更多有關針對谷氨酸系統 (glutamate)的新療法,可按此參閱詳情,或直接聯絡查詢。

I want to treat OCD

留言: Dear Dr Chan, 

I’ve been suffering from obsessive compulsive disorder (OCD,強迫症) for years and recently my situation has worsened to a point that I’d like to seek professional help. I’d like to ask a few questions about your treatment plans regarding OCD. 

Firstly, are you experienced in treating OCD patients? Secondly, are you qualified and experienced in using cognitive behavioral therapy and use cognitive behavioral therapy on your patients? And if so what kind of CBT methods do you use on OCD patients? Thirdly, what is your success rate for treating OCD patients? 

Thank you.

Reply from Dr Chan Man Lui:

OCD is a common mental illness. However, The degree of severity varies greatly from mild disturbance of the living to severe disturbance that affects one’s daily functioning.

I have treated many OCD over years and most of them recovered completely. However, a minority of those very severe ones may not be completely cured. In general, the more severe the illness, the more difficult to be treated. The more long-standing Illness, the more difficult to be treated. Obsessive ruminations are more difficult to treat than compulsive acts in general.

As for using cognitive behavioral therapy (CBT,認知行為治療), The most common method used is graded exposure. Firstly, The therapist and the patient will jointly make a list of tasks of ascending difficulties. Then, the patient needs to carry it out the tasks from the least anxiety provoking item and working upwards.

Thanks

Dr Chan Man Lui, Doris

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