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港人壓力大,抑鬱症越趨普遍。若確診抑鬱症,患者有需要服用多種抗抑鬱藥物,必要時或需加大劑量。當服用兩種或以上一定劑量的抗抑鬱藥物,並持續一段時間,治療效果卻不甚理想時,醫學上便稱為「難治型抑鬱症」。統計顯示,有關病人佔抑鬱症患者多達三分一,絕對不容忽視。

現時醫學界積極發開發針對谷氨酸系統 (glutamate)的新抗抑鬱藥物。透過雙管齊下的藥物治療方案,對比過去30年的主要透過調節大腦中單胺系統(monoamine)抗抑鬱藥物,包括血清素多巴胺去甲腎上腺素的信號傳遞療法,臨床所見平均大約服用二至三星期才見效,而且並非對所有抑鬱症患者都能奏效之下,患者使用針對谷氨酸系統 (glutamate)的新抗抑鬱藥物有望在更短時間內減輕抑鬱情緒,得到緩解。

抑鬱症有多種治療方案,各有其成效、副作用及限制,患者應與自己的主診醫生商討,選用最合適的治療方案。若出現抑鬱症症狀便應儘早求助及求醫,及早治療處理症狀。

若想了解更多有關針對谷氨酸系統 (glutamate)的新療法,可按此參閱詳情,或直接聯絡查詢。

Hello Dr, I am from Poland

Hello, Doctor!
I am from Poland, Polish doctors cannot help.
The case is 12 years old.
I had problems with insomnia, the doctor prescribed Promazin, he recommended taking 2 or 3 tablets a day, 100 mg each. I took these amounts, but sleep did not appear at all, when you are awake for 10 days, you start to panic – I started taking more Promazin tablets (5 tablets) to make the drug “catch”. In the end, I started to fall asleep due to total fatigue and exhaustion of the body than from taking Promazine. But the side effects of taking Promazine appeared and continue, i.e. weakening of the brain, slower reactions, weaker concentration, “mudding“, etc.

Could the Doctor suggest a drug / drugs that would reverse the condition after taking Promazine?
Please tell me how to “get down to business”. I’m from Poland.

Thank you very much
Sincerely
L

Dear L,

As many of the insomnias has the underlying causes, if you only target at sleeping, it’s not going to help. The common causes are due to anxiety, depression, or even psychosis, attention deficit hyper activity disorder etc. so without seeing you, I really can’t recommend any kind of medication You should take.

If you are only 12, I guess this is the reason they prescribed this drug to you. This is essentially an  antihistamine. By using The side effects of the anti-histamine, it will give you a feeling of sleepiness. But of course there will be severe hangover and drowsiness the next day.

Therefore, you better see your psychiatrist and ask for a further assessment, and tell him the hangover problem. 

Dr Chan Man Lui

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